The United captain has not featured in a match since September after liking a social media post that called for Mourinho to be sacked.
Valencia publicly apologised immediately and then spoke to Mourinho directly, but still found himself out in the cold under his manager.
Valencia’s agents sat down with United this week to discuss his future, as the defender continues to wait for a new contract offer.
But it seems the 33-year-old has now accepted his relationship with Mourinho is beyond repair.
Despite his difficulties with Mourinho, Valencia is in line to play against Liverpool on Sunday after United were hit with a host of injury concerns.
Defenders, Diogo Dalot, Matteo Darmian and Luke Shaw are all battling injuries and Valencia is set to keep his place after playing against Valencia in the Champions League mid-week. SHARE THIS STORY USING ANY OF THE BUTTON BELOW ⬇ PLACE YOUR TEXT ADVERT BELOW ⬇⬇⬇