His wife, Lerato Sengadi, told South Africa’s TimeLive news site: "Yes, yes it's true. I am with the family at the moment.”
There’s been an outpouring of messages of condolence on Twitter and the hashtag #RIPHHP is trending.
The BBC's Pumza Fihlani in Johannesburg says HHP is considered by many as the man who, using local languages, made South African hip hop mainstream and popular at a time when artists were imitating US-style rap.
He helped create a new sound that still inspires up-and-coming musicians today, she says.