He says “it seems the unorthodox approach worked, with researchers identifying two unique pathways that can lead to the development of new, more targeted cancer therapies.
“One of these ncRNA genes, named GUARDIN, is a molecule that helps to stabilise a particular protein involved in the DNA repair process and we discovered the protective mechanisms of GUARDIN were twofold.
“On one hand, it acts like a sponge to absorb harmful molecules, on the other, it functions like a bridge that brings two proteins together to protect the genome.”
The lead investigator said researchers found that reducing GUARDIN actually made cancer cells become more vulnerable to drug treatments, saying the second major breakthrough revealed that another ncRNA that regulates the metabolism of a cell accelerated the metabolic activity of cancer cells.
Co-author of the study, Dr Rick Thorne from University of Newcastle, explained that “while normal cells use up oxygen for energy, cancer cells use a process called glycolysis to produce energy.
“On face value, glycolysis is not a particularly efficient way for cancer cells to make energy but there are other advantages, for example, producing building blocks that enable cell growth.
“Like flicking a switch, we were encouraged that when we blocked this particular ncRNA, the cancer cell growth was also blocked and it began to revert to behave more like normal cells.” (Xinhua/NAN) THINK YOUR FRIEND WOULD BE INTRESTED? SHARE THIS STORY USING ANY OF THE SHARE BUTTON BELOW ⬇ PLACE YOUR TEXT ADVERT BELOW:>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> ( FREE ) secret Fruits that Increased My Manhood size and Lasting Power in 7-days... CLICK HERE TO GET IT