A 6-3 aggregate victory over Hoffenheim, completed on Wednesday, clinched a return to the Champions League but did not appear to take its toll on Liverpool, who were full of energy as they punished a shambolic display from Arsenal.
Arsene Wenger shuffled his back three after last weekend's dismal 1-0 defeat at Stoke City but they were left exposed when Liverpool regained possession high up the pitch and Roberto Firmino headed in the opener.
The visitors were caught out again when Sadio Mane finished off a move that flew from one box to the other and some woeful defending from the bungling Hector Bellerin allowed Mohamed Salah to surge clear to put the result beyond doubt in the second half.
Daniel Sturridge, a 74th-minute replacement for Mane, added gloss to a scoreline that will help overshadow the confusion regarding Simon Mignolet being dropped from the matchday squad as Loris Karius started his first top-flight game since December.
Despite the return of star forward Alexis Sanchez to the starting line-up after an abdominal injury Arsenal were left to mull on another chastening defeat that leaves them with just one win from their first three games.
Danny Welbeck led the Arsenal line ahead of Alexandre Lacazette and wasted a glorious chance to repay Wenger's faith when he lost his footing and fired over under pressure from Joe Gomez.
Salah would have similarly been ruing his finishing in the 10th minute. Emre Can burst into the box via a one-two with Firmino and rolled a cross to the back post for the Egyptian, whose shot along the ground was blocked brilliantly by Petr Cech at full stretch. PLACE YOUR TEXT ADVERT BELOW:>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> How I Made Me =N=2.5 MILLION In 7 Days from 2 Common Product I Imported and how you can do the same. Click HERE FOR FREE Details right now Warning To Men: This 3 Foods Is Killing Your Erection. Click Here To Know Them Secret Fruits that increased my Manhood and makes me last 55 minutes+ all time - Click here to get it Warning: Got Arthritis? 3 Simple Ways To Get Cured And Be Permanently Free From Joint Pains. Click Here To See Them REVEALED!! Reduce Your Blood Sugar Level And Reverse Diabetics Within A Short Period Of Time. Click Here To See How MIDNIGHT,Pressed Mr Kilanko Suddenly Couldn't Urinate. Shrink your Enlarged Prostrate Here! Click Here Now