They died after eating potato chips and drinking water from a tap.
According to Daily Sun SA, Supra Mahumapelo, the Premier of North West, on Wednesday said he was saddened by the deaths of the two siblings who fell sick.
Daily Sun SA reports that the kids passed away after eating potato chips and drinking tap water from a 25-litre container.
The siblings, two boys aged 10 and 12 from Makgobistad, died on Tuesday afternoon.
It was not immediately clear what had caused their deaths.
Mahumapelo said the two boys were pupils at Makgobi Primary School.
School teacher Cathrine Marumo said the school was told they fell sick after eating potato chips and drinking tap water from a 25-litre container at home in the late afternoon.
They later died at a local clinic.
A total of three children from the same family were affected.
The third child, a 15-year-old, was recovering at the Bophelong Hospital in Mahikeng.
Mahumapelo said: "We send our heartfelt condolences to the family affected by this tragedy. We will do whatever we can do from our side to provide support to the family during this difficult time."
School principal Lesedi Modise said a memorial service had been planned for Thursday at the Makgobistad Community Hall at 11:30. PLACE YOUR TEXT ADVERT BELOW:>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> How I Made Me =N=2.5 MILLION In 7 Days from 2 Common Product I Imported and how you can do the same. Click HERE FOR FREE Details right now Warning To Men: This 3 Foods Is Killing Your Erection. Click Here To Know Them Secret Fruits that increased my Manhood and makes me last 55 minutes+ all time - Click here to get it Warning: Got Arthritis? 3 Simple Ways To Get Cured And Be Permanently Free From Joint Pains. Click Here To See Them REVEALED!! Reduce Your Blood Sugar Level And Reverse Diabetics Within A Short Period Of Time. Click Here To See How MIDNIGHT,Pressed Mr Kilanko Suddenly Couldn't Urinate. Shrink your Enlarged Prostrate Here! Click Here Now