His death comes two weeks after he suffered a stroke.
Doctors had said Mr Peres had made some progress but his condition deteriorated rapidly on Tuesday.
Mr Peres held nearly every major office in Israel – serving twice as prime minister and also as president between 2007 and 2014.
He won the 1994 Nobel Peace Prize jointly with prime minister Yitzhak Rabin and Palestinian leader Yasser Arafat for his role in negotiating the Oslo Accords, which envisioned an independent Palestinian state.
Mr Peres died in a hospital near Tel Aviv early on Wednesday, with his family at his bedside.
He had been in the intensive care unit of the Sheba Medical Centre after suffering a major stroke on 13 September.
Israel's Prime Minister Benjamin Netanyahu expressed his "deep personal grief on the passing of the beloved of the nation".
Meanwhile US President Barack Obama called Mr Peres his "dear friend" in a statement, and said: "He was guided by a vision of the human dignity and progress that he knew people of goodwill could advance together."
Mr Peres shared his Nobel Peace Prize with Prime Minister Yitzhak Rabin, who was later assassinated, and Palestinian leader Yasser Arafat. PLACE YOUR TEXT ADVERT BELOW:>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> How I Made Me =N=2.5 MILLION In 7 Days from 2 Common Product I Imported and how you can do the same. Click HERE FOR FREE Details right now Warning To Men: This 3 Foods Is Killing Your Erection. Click Here To Know Them Secret Fruits that increased my Manhood and makes me last 55 minutes+ all time - Click here to get it Warning: Got Arthritis? 3 Simple Ways To Get Cured And Be Permanently Free From Joint Pains. Click Here To See Them REVEALED!! Reduce Your Blood Sugar Level And Reverse Diabetics Within A Short Period Of Time. Click Here To See How MIDNIGHT,Pressed Mr Kilanko Suddenly Couldn't Urinate. Shrink your Enlarged Prostrate Here! Click Here Now